Dextromethorphan, phenylephrine, and pyrilamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any other medicine without first talking to your doctor.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

Pyrilamine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Pyrilamine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Dextromethorphan is a cough suppressant. It suppresses an area in the brain that causes coughing.

Phenylephrine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries). This reduces the blood flow, which decreases swelling and allows nasal and respiratory (breathing) passages to open up.

Dextromethorphan, phenylephrine, and pyrilamine is used to treat nasal congestion, sinusitis (inflammation of the sinuses), and coughs associated with allergies, hay fever, and the common cold.

Dextromethorphan, phenylephrine, and pyrilamine may also be used for purposes other than those listed in this medication guide